IIFT
cell nuclei
(ANA global test)
HEp-2 cells
liver
(2 BIOCHIPs per field)
human
monkey
IIFT
cell nuclei (ANA) EUROPattern
cell nuclei (ANA)
HEp-2 cells
liver
(2 BIOCHIPs per field)
human
monkey
IIFT
cell nuclei (ANA)
mitochondria (AMA)
HEp-2 cells
kidney
(2 BIOCHIPs per field)
human
rat
IIFT
cell nuclei
(ANA global test)
HEp-20-10 cells
liver
(2 BIOCHIPs per field)
human
monkey
IIFT
cell nuclei (ANA) EUROPattern
cell nuclei (ANA)
HEp-20-10 cells
liver
(2 BIOCHIPs per field)
human
monkey
IIFT
cell nuclei (ANA)
mitochondria (AMA)
HEp-20-10 cells
kidney
(2 BIOCHIPs per field)
human
rat
IIFT
cell nuclei (ANA) EUROPattern
mitochondria (AMA)
HEp-20-10 cells
kidney
(2 BIOCHIPs per field)
human
rat
IIFT
cell nuclei (ANA)
HEp-2 cells
human
IIFT
cell nuclei (ANA)
EUROPattern
HEp-2 cells
human
IIFT
cell nuclei (ANA)
HEp-20-10 cells
human
IIFT
cell nuclei (ANA)
EUROPattern
HEp-20-10 cells
human
EUROLINE
positive control serum: IgG, human, 100x concentrated
for DL 1530-X G
EUROLINE
Myositis Profile
(Mi-2, Ku, PM-Scl, Jo-1, PL-7,
PL-12, Ro-52 separately)
EUROLINE
EUROLINE
Myositis Profile 3
(Mi-2, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP,
PL-7, PL-12, EJ, OJ, Ro-52 separately)
EUROLINE
EUROLINE
Autoimmune Inflammatory Myopathies 16 Ag
(Mi-2 alpha, Mi-2 beta, TIF1g, MDA5, NXP2, SAE1, Ku, PM-Scl100,
PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro-52 separately)
EUROLINE
EUROLINE
Autoimmune Inflammatory Myopathies 16 Ag et cN-1A
(Mi-2 alpha, Mi-2 beta, TIF1g, MDA5, NXP2, SAE1, Ku,
PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ,
Ro-52, cN-1A separately)
EUROLINE
EUROLINE
Autoimmune Inflammatory Myopathies 20 Ag
( Mi-2 alpha, Mi-2 beta, TIF1g, MDA5, NXP2, SAE1,
Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ,
Ro-52, cN-1A, Ha, Ks, Zo)
EUROLINE
EUROLINE
positive control serum: IgG, human, 100x concentrated
for DL 1532 G
EUROLINE
Systemic Sclerosis Profile (Nucleoli)
(Scl-70, CENP A, CENP B, RP11, RP155,
fibrillarin, NOR90, Th/To, PM-Scl100, PM-Scl75,
Ku, PDGFR, Ro-52 separately)
EUROLINE
EUROLINE
Systemic Sclerosis Profile 2
(Scl-70, CenpA, Cenp B, RP11, RP155,
Fibrillarin, NOR90, Th/To, PM-Scl100, PM-Scl75,
Ku, NVL und Ro-52)
EUROLINE
ELISA
histones
antigen-coated
microplate wells
IIFT
antibodies against cell nuclei
(ANA control), homogeneous pattern
ELISA
double-stranded DNA
(dsDNA)
antigen-coated
microplate wells
ChLIA
IDS dsDNA IgG 1
antigenic coated magnetic particles
IIFT
antibodies against dsDNA
(dsDNA ab control)
ELISA
dsDNA-NcX
antigen-coated
microplate wells
IIFT
dsDNA
flagellates
Crithidia luciliae
IIFT
dsDNA
EUROPattern
flagellates
Crithidia luciliae
IIFT
dsDNA (sensitive)
flagellates
Crithidia luciliae
IIFT
dsDNA (sensitive)
EUROPattern
flagellates
Crithidia luciliae
ELISA
nucleosomes
antigen-coated
microplate wells
ELISA
single-stranded DNA
(ssDNA)
antigen-coated
microplate wells
ELISA
PM-Scl
antigen-coated
microplate wells
EUROLINE
positive control serum: IgG, human, 100x concentrated
for DL 1590-X G
ChLIA
IDS ENA Screen 1
antigenic coated magnetic particles
ChLIA
IDS ANA Control Set 1
3 x 1.5mL Control 1/2
EUROASSAY
Anti-ENA ProfilePlus
(nRNP/Sm, Sm, SS-A, SS-B, Scl-70,
Jo-1 separately)
EUROASSAY strip
with antigens
EUROLINE
Anti-ENA ProfilePlus 1
(nRNP/Sm, Sm, SS-A, Ro-52, SS-B,
Scl-70, Jo-1 separately)
EUROLINE
ELISA
Anti-ENA ProfilePlus 1 (nRNP/Sm,
Sm, SS-A, SS-B, Scl-70, Jo-1 separately)
antigen-coated
microplate wells
ChLIA
IDS ANA Screen 1
antigenic coated magnetic particles
ELISA
ANA screen 11 (antigen mixture: PCNA,
PM-Scl, ribosomal P-proteins, nRNP/Sm,
Sm, SS-A, Ro-52, SS-B, Scl-70, Jo-1,
centromeres)
antigen-coated
microplate wells
ELISA
Anti-ENA SLE Profile 2 (dsDNA, histones,
nucleosomes, nRNP/Sm, Sm,
SS-A, SS-B, Scl-70 separately)
antigen-coated
microplate wells
ELISA
ANA screen 9 (antigen mixture: PCNA,
PM-Scl, ribosomal P-proteins, nRNP/Sm,
Sm, SS-A, SS-B, Scl-70, Jo-1)
antigen-coated
microplate wells
ChLIA
IDS ANA Screen Control Set 1
3 x 1.5mL Control 1/2
ELISA
Anti-ENA ProfilePlus 2 (ribosomal
P-proteins, nRNP/Sm, Sm, SS-A, SS-B,
Scl-70, Jo-1, centromeres, separately)
antigen-coated
microplate wells
EUROASSAY
Anti-ENA ProfilePlus with histones
(nRNP/Sm, Sm, SS-A, SS-B, Scl-70,
Jo-1, histones separately)
EUROASSAY strip
with antigens
EUROLINE
ANA Profile 23
(nucleosomes, dsDNA, histones, SS-A, Ro-52,
SS-B, nRNP/Sm, Sm, Mi-2 alpha, Mi-2 beta, Ku, CENP A,
CENP B, Sp100, PML, Scl-70, PM-Scl100, PM-Scl75,
RP11, RP155, gp210, PCNA, DFS70 separately)
EUROLINE
EUROLINE
ANA Profile 3
(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70, PM-Scl,
Jo-1, CENP B, PCNA, dsDNA, nucleosomes,
histones, ribosomal P-proteins, AMA M2 separately)
EUROLINE
EUROLINE
ANA Profile 3 plus DFS70
(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70, PM-Scl,
Jo-1, CENP B, PCNA, dsDNA, nucleosomes, histones,
ribosomal P-proteins, AMA M2, DFS70 separately)
EUROLINE
EUROLINE
ANA Profile et Mi-2 et Ku
(Mi-2, Ku, nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70,
PM-Scl, Jo-1, CENP B, PCNA, dsDNA, nucleosomes,
histones, ribosomal P-proteins, AMA M2 separately)
EUROLINE
EUROLINE
dsDNA, nucleosomes, histones, DFS70
EUROLINE
EUROLINE
ANA Profile et Mi-2, Ku, DFS70
(Mi-2, Ku, nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70,
PM-Scl100, Jo-1, CENP B, PCNA, dsDNA,
nucleosomes, histones, ribosomal P-proteins,
AMA M2, DFS70 separately)
EUROLINE
EUROLINE
positive control serum: IgG, human, 100x concentrated
for DL 1590-35 G
EUROLINE
Cytoplasm profile
(AMA M2, M2-3E, ribosomal P-proteins, Jo-1
SRP, PL-7, PL-12, EJ, OJ, Ro-52 separately)
EUROLINE
EUROLINE
Cytoplasm Profile 13 Ag
CAMA-M2, M2-3E, ribosomale P-Proteine,
Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro-52, Ha, Ks, Zo)
EUROLINE
EUROLINE
ANA Profile 5
(nRNP/Sm, Sm, RNP70, RNPA, RNPC, SS-A,
Ro-52, SS-B, Scl-70, PM-Scl, Jo-1, CENP B,
PCNA, dsDNA, nucleosomes, histones,
ribosomal P-proteins, AMA M2 separately)
EUROLINE
ELISA
Anti-ENA PoolPlus (antigen mixture:
nRNP/Sm, Sm, SS-A, SS-B, Scl-70, Jo-1)
antigen-coated
microplate wells
EUROLINE
ANA Profile 1
(nRNP/Sm, Sm, SS-A, Ro-52, SS-B, Scl-70,
Jo-1, CENP B, dsDNA, nucleosomes, histones,
ribosomal P-proteins separately)
EUROLINE
ELISA
ANA screen (antigen mixture: dsDNA,
histones, ribosomal P-proteins, nRNP/Sm,
Sm, SS-A, SS-B, Scl-70, Jo-1, centromeres)
antigen-coated
microplate wells
ELISA
Anti-ENA Pool (antigen mixture:
nRNP/Sm, Sm, SS-A, SS-B, Scl-70,
ribosomal P-proteins, Ro-52)
antigen-coated
microplate wells
ELISA
nRNP/Sm
antigen-coated
microplate wells
ChLIA
IDS U1-snRNP 1
antigenic coated magnetic particles
ELISA
Sm
antigen-coated
microplate wells
ChLIA
IDS Sm 1
antigenic coated magnetic particles
ELISA
SS-A (Ro)
antigen-coated
microplate wells
ChLIA
IDS SS-A/Ro 1
antigenic coated magnetic particles
ChLIA
IDS SS-A/Ro 52 kDa 1
antigenic coated magnetic particles
ChLIA
IDS SS-A/Ro 60 kDa 1
antigenic coated magnetic particles
ELISA
SS-B (La)
antigen-coated
microplate wells
ChLIA
IDS SS-B/La 1
antigenic coated magnetic particles
ELISA
Scl-70
antigen-coated
microplate wells
ChLIA
IDS Scl-70 1
antigenic coated magnetic particles
EUROLINE
positive control serum: IgG, human, 100x concentrated
for DL 159z-X G
EUROLINE
EUROLINE Anti-DFS70
EUROLINE
ELISA
DFS70
antigen-coated
microplate wells
ELISA
centromeres
antigen-coated
microplate wells
ChLIA
IDS Centromere B 1
antigenic coated magnetic particles
ELISA
ribosomal P-proteins
antigen-coated
microplate wells
ELISA
Jo-1
antigen-coated
microplate wells
ChLIA
IDS Jo-1 1
antigenic coated magnetic particles
ELISA
cN-1A (Mup44, NT5C1A)
antigen-coated
microplate wells
![]({"large":"/typo3conf/ext/typoconfiguration/Resources/Public/Images/icons/magnifying_glass_white.svg","medium":"/typo3conf/ext/typoconfiguration/Resources/Public/Images/icons/magnifying_glass_white.svg","small":"/typo3conf/ext/typoconfiguration/Resources/Public/Images/icons/magnifying_glass_white.svg"}){kind=icon}
La méthode de référence pour la détection des ANA est le test d’immunofluorescence indirecte (IFI) avec des cellules épithéliales humaines (HEp-2), connu pour sa grande sensibilité et spécificité. L’évaluation au microscope permet de déterminer avec précision comment un colorant indicateur (généralement la fluorescéine) se répartit dans les cellules. En fonction de la localisation des différents autoantigènes, chaque type d’auto-anticorps lié donne un aspect de fluorescence typique.
